Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 8/20 | 0.48 |
| ▸ | RXRB | P28702 | 7/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 13/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | C5 | P01031 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006866 | 0.98 | PTGIR (0.51) | PTGIRRXRARXRBNR4A2NR4A1 | |
| SCHEMBL9006859 | 0.91 | PTGIR (0.48) | PTGIRRXRARXRBNR4A2NR4A1 | |
| SCHEMBL9006861 | 0.89 | PTGIR (0.50) | PTGIRRXRARXRBNR4A2NR4A1 | |
| SCHEMBL8075431 | 0.87 | RXRA (0.55) | PTGIRRXRARXRBNR4A2NR4A1 | |
| SCHEMBL8056893 | 0.86 | PTGIR (0.58) | PTGIRRXRARXRBNR4A2NR4A1 | |
| SCHEMBL8065101 | 0.85 | RXRA (0.55) | PTGIRRXRARXRBNR4A2NR4A1 | |
| SCHEMBL8069442 | 0.85 | PTGIR (0.60) | PTGIRRXRARXRBNR4A2NR4A1 | |
| SCHEMBL9006762 | 0.83 | PTGIR (0.71) | PTGIRRXRARXRBLMNAALDH1A1 | |
| SCHEMBL27320815 | 0.81 | NR4A2 (0.45) | PTGIRRXRARXRBNR4A2NR4A1 | |
| SCHEMBL9452960 | 0.77 | PPARD (0.56) | RXRARXRBNR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |