Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TYMP | P19971 | 11/20 | 0.63 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682944 | 0.80 | TYMP (0.65) | ALOX15TYMPPABPC1 | |
| SCHEMBL9006994 | 0.79 | TYMP (0.63) | ALOX15TYMPPABPC1MAPT | |
| SCHEMBL1682985 | 0.79 | TYMP (0.63) | ALOX15TYMPMAPT | |
| SCHEMBL1682926 | 0.75 | TYMP (0.59) | ALOX15TYMP | |
| SCHEMBL1691006 | 0.75 | TYMP (0.58) | ALOX15TYMPPABPC1MAPTALDH1A1 | |
| SCHEMBL20799905 | 0.74 | TYMP (0.70) | ALOX15TYMPMAPTALDH1A1KDM4E | |
| SCHEMBL14388457 | 0.71 | PNP (0.51) | ALOX15TYMP | |
| Hydrochloric Acid SCHEMBL10927079 | 0.69 | ALOX15 (0.54) | ALOX15TYMPMAPTL3MBTL1ABL1 | |
| SCHEMBL25344146 | 0.69 | TYMP (0.46) | ALOX15TYMPL3MBTL1 | |
| SCHEMBL6570508 | 0.69 | TYMP (0.46) | ALOX15TYMPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188105-B2 | Therapeutic agent for inflammatory bowel disease comprising uracil derivative as active ingredient | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2012-05-29 | — | — | US | disclosed |