Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.41 |
| ▸ | RXRB | P28702 | 5/20 | 0.41 |
| ▸ | PTGIR | P43119 | 6/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 11/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | C5 | P01031 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006849 | 0.85 | NR4A2 (0.42) | RXRARXRBPTGIRNR4A2NR4A1 | |
| SCHEMBL9006922 | 0.78 | PTGIR (0.51) | RXRARXRBPTGIRNR4A2NR4A1 | |
| SCHEMBL9006842 | 0.77 | NR4A2 (0.41) | RXRARXRBPTGIRNR4A2NR4A1 | |
| SCHEMBL9006904 | 0.77 | RXRA (0.47) | RXRARXRBPTGIRNR4A2NR4A1 | |
| SCHEMBL9006890 | 0.77 | PTGIR (0.51) | RXRARXRBPTGIRNR4A2NR4A1 | |
| SCHEMBL8065990 | 0.75 | FABP4 (0.50) | PTGIRKDM4ECYP3A4HPGDTBXA2R | |
| SCHEMBL8065993 | 0.75 | FABP4 (0.50) | PTGIRKDM4ECYP3A4HPGDTBXA2R | |
| SCHEMBL9006895 | 0.74 | NR4A2 (0.54) | RXRARXRBPTGIRNR4A2NR4A1 | |
| SCHEMBL9452960 | 0.74 | PPARD (0.56) | RXRARXRBNR4A2NR4A1NR4A3 | |
| SCHEMBL9006820 | 0.73 | RXRA (0.45) | RXRARXRBPTGIRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |