Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 12/20 | 0.69 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772579 | 1.00 | ADRB1 (0.69) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL9006832 | 1.00 | ADRB1 (0.69) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL6553102 | 0.93 | ADRB3 (0.61) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL6553106 | 0.93 | ADRB3 (0.61) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL6541299 | 0.92 | ADRB3 (0.60) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL11053844 | 0.90 | ADRB3 (0.56) | ADRB1ADRB3ADRB2SLC2A1ADRA1A | |
| SCHEMBL9007073 | 0.90 | ADRB3 (0.56) | ADRB1ADRB3ADRB2SLC2A1ADRA1A | |
| SCHEMBL9007077 | 0.90 | ADRB3 (0.56) | ADRB1ADRB3ADRB2SLC2A1ADRA1A | |
| SCHEMBL10773274 | 0.89 | ADRB1 (0.60) | ADRB1ADRB3ADRB2SLC2A1ADRA1A | |
| Hydrochloric Acid SCHEMBL11040417 | 0.89 | ADRB3 (0.55) | ADRB1ADRB3ADRB2SLC2A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403360-B1 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI SA (FR) | 1996-10-16 | — | — | EP | claimed |
| EP-0255415-B1 | USE OF PHENYLETHANOLAMINES FOR THE PREPARATION OF MEDICAMENTS ACTING ON GASTROINTESTINAL TROUBLES | ELF SANOFI (FR) | 1993-04-14 | — | — | EP | claimed |