Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PDXK | O00764 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608947 | 0.74 | SHBG (0.52) | SHBGKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27984345 | 0.72 | SHBG (0.50) | SHBGKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7522113 | 0.71 | SHBG (0.48) | SHBGKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7526681 | 0.70 | CA1 (0.33) | SHBGKDM4EALDH1A1LMNACA1 | |
| SCHEMBL28585139 | 0.70 | SHBG (0.42) | SHBGKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13866611 | 0.69 | KDM4E (0.48) | SHBGKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14283816 | 0.69 | SHBG (0.45) | SHBGKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5680646 | 0.68 | SELL (0.34) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL25328340 | 0.67 | ESR1 (0.39) | SHBGKDM4EMAOACA1CA2 | |
| SCHEMBL2219441 | 0.67 | SHBG (0.48) | SHBGKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732928-A1 | METHOD OF LOWERING SERUM CHOLESTEROL LEVELS WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015760-A1 | METHOD OF LOWERING SERUM CHOLESTEROL LEVELS WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS | MERRELL PHARMACEUTICALS INC. (US) | 1995-06-15 | — | — | WO | disclosed |