Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900207 | 0.83 | SMN1; SMN2 (0.34) | PDE2ASMN1; SMN2ACHELMNAKCNK2 | |
| SCHEMBL26020034 | 0.83 | ACHE (0.32) | SMN1; SMN2ACHELMNAMCL1ALDH1A1 | |
| SCHEMBL10987403 | 0.81 | HAO1 (0.40) | PDE2ASMN1; SMN2LMNAALDH1A1TDP1 | |
| SCHEMBL16707555 | 0.79 | SMN1; SMN2 (0.49) | PDE2ASMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL31693443 | 0.78 | ACHE (0.35) | ACHEKDM4EPTGS1PTGS2 | |
| SCHEMBL10525468 | 0.78 | PDE2A (0.46) | PDE2AKCNK2KDM4EALDH1A1TDP1 | |
| SCHEMBL576125 | 0.78 | SLC6A2 (0.39) | ACHELMNAKDM4E | |
| SCHEMBL576541 | 0.78 | ACHE (0.38) | ACHEKDM4EALDH1A1PTGS1PTGS2 | |
| SCHEMBL9694900 | 0.78 | ESR2 (0.37) | PDE2ASMN1; SMN2ACHELMNAALDH1A1 | |
| SCHEMBL18856709 | 0.78 | ALDH1A1 (0.47) | PDE2ASMN1; SMN2LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |