Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.43 |
| ▸ | PGR | P06401 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007387 | 1.00 | AR (0.43) | ARPGRLMNASLC6A4ESR1 | |
| SCHEMBL10627295 | 0.83 | PGR (0.60) | ARPGRLMNASLC6A4ESR1 | |
| SCHEMBL9222367 | 0.81 | AR (0.39) | ARPGRLMNASLC6A4ESR1 | |
| SCHEMBL9222376 | 0.81 | AR (0.39) | ARPGRLMNASLC6A4ESR1 | |
| SCHEMBL9217652 | 0.81 | AR (0.37) | ARPGRLMNASLC6A4ESR1 | |
| SCHEMBL9217656 | 0.81 | AR (0.37) | ARPGRLMNASLC6A4ESR1 | |
| SCHEMBL9007360 | 0.78 | LMNA (0.41) | ARPGRLMNASLC6A4ESR1 | |
| SCHEMBL9007369 | 0.78 | LMNA (0.41) | ARPGRLMNASLC6A4ESR1 | |
| SCHEMBL9007381 | 0.77 | PGR (0.71) | ARPGRLMNASLC6A4ESR1 | |
| SCHEMBL9007376 | 0.77 | PGR (0.71) | ARPGRLMNASLC6A4ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538348-B1 | UNSATURATED 15-DEHYDRO-17alpha-CYANOMETHYL-17beta- HYDROXYSTEROIDS | JENAPHARM GMBH (DE) | 1996-10-02 | — | — | EP | disclosed |
| US-5438134-A | Endocrine disorders, reproductive control | JENAPHARM GMBH (DE) | 1995-08-01 | — | — | US | disclosed |
| WO-1992000991-A1 | PROCESS FOR PRODUCING UNSATURATED 17-ALPHA-CYANOMETHYL-17-BETA-HYDROXYSTEROIDS | JENAPHARM GMBH (DE) | 1992-01-23 | — | — | WO | disclosed |