Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 5/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007403 | 1.00 | ESR1 (0.48) | ESR1LMNANR3C1PGRCYP1A2 | |
| SCHEMBL9007385 | 0.89 | STS (0.51) | ESR1LMNANR3C1PGRCYP1A2 | |
| SCHEMBL9007380 | 0.89 | STS (0.51) | ESR1LMNANR3C1PGRCYP1A2 | |
| SCHEMBL9007383 | 0.87 | ESR1 (0.57) | ESR1LMNANR3C1PGRCYP1A2 | |
| SCHEMBL9007351 | 0.87 | ESR1 (0.57) | ESR1LMNANR3C1PGRCYP1A2 | |
| SCHEMBL7129419 | 0.80 | LMNA (0.55) | ESR1LMNANR3C1PGRCYP1A2 | |
| SCHEMBL9007360 | 0.76 | LMNA (0.41) | ESR1LMNANR3C1PGRCYP3A4 | |
| SCHEMBL11868500 | 0.75 | ESR1 (0.59) | ESR1LMNANR3C1PGRCYP1A2 | |
| SCHEMBL9007378 | 0.75 | ABCB11 (0.59) | ESR1NR3C1PGRCYP3A4SLC6A2 | |
| SCHEMBL9007386 | 0.75 | ABCB11 (0.59) | ESR1NR3C1PGRCYP3A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538348-B1 | UNSATURATED 15-DEHYDRO-17alpha-CYANOMETHYL-17beta- HYDROXYSTEROIDS | JENAPHARM GMBH (DE) | 1996-10-02 | — | — | EP | claimed |
| WO-1992000991-A1 | PROCESS FOR PRODUCING UNSATURATED 17-ALPHA-CYANOMETHYL-17-BETA-HYDROXYSTEROIDS | JENAPHARM GMBH (DE) | 1992-01-23 | — | — | WO | claimed |
| US-5438134-A | Endocrine disorders, reproductive control | JENAPHARM GMBH (DE) | 1995-08-01 | — | — | US | disclosed |