Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | LIPE | Q05469 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27910258 | 0.90 | MAPT (0.67) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL19612191 | 0.89 | MAPT (1.00) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL31725934 | 0.89 | MAPT (0.65) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL4469014 | 0.89 | MAPT (0.65) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL9340084 | 0.89 | MAPT (0.65) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL24819317 | 0.86 | MAPT (0.61) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL31613048 | 0.85 | MAPT (0.65) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL9540402 | 0.84 | L3MBTL1 (0.67) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL15668933 | 0.84 | MAPT (0.59) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL24968079 | 0.84 | L3MBTL1 (0.63) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506361-A | ACTS BOTH AS AN ANGIOTENSIN II ANTAGONIST AND A LIPIDPEROXIDATION INHIBITOR | THEUPJOHN COMPANY (US) | 1996-04-09 | — | — | US | disclosed |
| WO-1992019211-A2 | IMIDAZOBENZOQUINONES AND COMPOSITION FOR PREVENTING OR TREATING HYPERTENSION OR CONGESTIVE HEART FAILURE CONTAINING THE SAME | THE UPJOHN COMPANY (US) | 1992-11-12 | — | — | WO | disclosed |