Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341625 | 0.93 | L3MBTL1 (0.59) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL24983833 | 0.91 | PTGER1 (0.60) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL30141251 | 0.91 | PTGER1 (0.60) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL5467535 | 0.88 | PTGER1 (0.58) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL6286054 | 0.88 | L3MBTL1 (0.81) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL27550697 | 0.88 | PTGER1 (0.60) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL27703867 | 0.88 | L3MBTL1 (0.63) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL9336507 | 0.88 | MAPT (0.63) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL410077 | 0.87 | PTGER1 (0.76) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL31177876 | 0.86 | MCL1 (0.61) | L3MBTL1MAPTTDP1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002051-A1 | INDOLES | PFIZER LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |
| WO-1993002050-A1 | INDOLES | PFIZER LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |