Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007552 | 0.82 | GAA (0.40) | CYP19A1CYP11B1CYP11B2RXFP1LMNA | |
| SCHEMBL9007622 | 0.80 | CYP19A1 (0.42) | CYP19A1CYP11B1CYP11B2RXFP1LMNA | |
| SCHEMBL11745958 | 0.76 | GAA (0.61) | CYP19A1CYP11B1CYP11B2RXFP1LMNA | |
| Methane SCHEMBL10453459 | 0.75 | GAA (0.60) | CYP19A1CYP11B1CYP11B2RXFP1LMNA | |
| SCHEMBL6481148 | 0.69 | NCEH1 (0.54) | CYP19A1RXFP1LMNAKDM4EGAA | |
| SCHEMBL9136395 | 0.68 | NCEH1 (0.41) | CYP19A1CYP11B1CYP11B2RXFP1LMNA | |
| SCHEMBL4673038 | 0.67 | NCEH1 (0.49) | CYP19A1CYP11B1CYP11B2RXFP1LMNA | |
| SCHEMBL8164689 | 0.66 | CA12 (0.57) | CYP19A1CYP11B1CYP11B2LMNACA1 | |
| SCHEMBL9007503 | 0.65 | NCEH1 (0.48) | CYP19A1CYP11B1CYP11B2RXFP1LMNA | |
| SCHEMBL5979768 | 0.65 | CYP11B1 (0.62) | CYP19A1CYP11B1CYP11B2LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482968-A | ENZYME INHIBITORS, HYPOGLYCEMIC AGENTS AND VASCULAR AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-01-09 | — | — | US | disclosed |