Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 8/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007552 | 0.82 | GAA (0.40) | NCEH1LMNARXFP1PTGS1CYP19A1 | |
| SCHEMBL9007622 | 0.81 | CYP19A1 (0.42) | NCEH1LMNARXFP1CYP19A1CYP11B1 | |
| SCHEMBL11745958 | 0.70 | GAA (0.61) | NCEH1LMNARXFP1PTGS1CYP19A1 | |
| SCHEMBL9007503 | 0.69 | NCEH1 (0.48) | NCEH1LMNARXFP1CYP19A1CYP11B1 | |
| Methane SCHEMBL10453459 | 0.69 | GAA (0.60) | NCEH1LMNARXFP1PTGS1CYP19A1 | |
| SCHEMBL4673038 | 0.69 | NCEH1 (0.49) | NCEH1LMNARXFP1PTGS1CYP19A1 | |
| SCHEMBL20414572 | 0.69 | CFD (0.51) | NCEH1CFDLMNAPTGS1SMN1; SMN2 | |
| SCHEMBL6481148 | 0.68 | NCEH1 (0.54) | NCEH1LMNARXFP1CYP19A1SMN1; SMN2 | |
| SCHEMBL9007619 | 0.68 | CYP19A1 (0.42) | NCEH1LMNARXFP1CYP19A1CYP11B1 | |
| SCHEMBL9007497 | 0.68 | CYP19A1 (0.49) | NCEH1LMNARXFP1CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399588-A | Diabetes treatment | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |