Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373209 | 0.89 | ALOX15 (0.34) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL406816 | 0.89 | ALOX15 (0.34) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL30770673 | 0.87 | LMNA (0.33) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL9007662 | 0.81 | LMNA (0.32) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL26698111 | 0.81 | LMNA (0.30) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL14423397 | 0.79 | LMNA (0.33) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL11129316 | 0.78 | ALOX15 (0.36) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL29871222 | 0.78 | ALOX15 (0.36) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL7949644 | 0.78 | LMNA (0.32) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL31572308 | 0.78 | ALOX15 (0.36) | LMNATP53CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516006-B1 | 4,4'-Biphenylenediphosphonite compound and use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-10-23 | — | — | EP | claimed |
| EP-0516006-B1 | 4,4'-Biphenylenediphosphonite compound and use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-10-23 | — | — | EP | disclosed |