Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | BHMT | Q93088 | 3/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355106 | 0.85 | CA2 (0.59) | CA2MAPK1FOLH1CA1GRIK1 | |
| SCHEMBL2354888 | 0.84 | CA2 (0.61) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL3820505 | 0.76 | CA2 (0.54) | CA2MAPK1FOLH1THRBCA1 | |
| SCHEMBL14567449 | 0.76 | CHRM1 (0.50) | CA2MAPK1FOLH1GRIK1GRIK2 | |
| SCHEMBL11374133 | 0.76 | CA2 (0.52) | CA2MAPK1THRBCA1CHRM1 | |
| SCHEMBL25996488 | 0.76 | ALDH1A1 (0.38) | POLBMAPTTHRBPLA2G4BTDP1 | |
| SCHEMBL8771201 | 0.76 | GRIK1 (0.53) | CA2MAPK1MAPTGRIK1GRIK2 | |
| SCHEMBL5361363 | 0.76 | CA2 (0.55) | CA2MAPK1MAPTCA1GRIK1 | |
| SCHEMBL9007929 | 0.76 | TSHR (0.50) | BHMTHSD17B10PLA2G4BTDP1 | |
| SCHEMBL11068865 | 0.76 | GRIK1 (0.53) | CA2MAPK1MAPTGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571689-A | Method of N-acylating peptide and proteins with diheteroatom substituted analogs of myristic acid | WASHINGTON UNIVERSITY (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0441765-B1 | Novel fatty acid analog enzyme substrates | UNIV WASHINGTON (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5082967-A | Myristolyation | WASHINGTON UNIVERSITY (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0441765-A1 | Novel fatty acid analog enzyme substrates | WASHINGTON UNIVERSITY (US) | 1991-08-14 | — | — | EP | disclosed |