Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.54 |
| ▸ | GLO1 | Q04760 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007852 | 1.00 | PTGS1 (0.54) | PTGS1GSTK1GLO1MAPTADAM17 | |
| SCHEMBL9007849 | 0.85 | PTGS1 (0.59) | PTGS1GSTK1GLO1LTA4H | |
| SCHEMBL11869437 | 0.82 | PTGS1 (0.54) | PTGS1GSTK1GLO1MAPT | |
| SCHEMBL11871343 | 0.82 | PTGS1 (0.54) | PTGS1GSTK1GLO1MAPT | |
| SCHEMBL3280191 | 0.79 | GLO1 (0.60) | PTGS1GSTK1GLO1LTA4H | |
| SCHEMBL3280199 | 0.79 | GLO1 (0.60) | PTGS1GSTK1GLO1LTA4H | |
| SCHEMBL4230290 | 0.79 | PTGS1 (0.57) | PTGS1GSTK1GLO1LTA4H | |
| SCHEMBL4230298 | 0.79 | PTGS1 (0.57) | PTGS1GSTK1GLO1LTA4H | |
| SCHEMBL5332441 | 0.79 | PTGS1 (0.68) | PTGS1GSTK1GLO1 | |
| SCHEMBL5332446 | 0.79 | PTGS1 (0.68) | PTGS1GSTK1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536231-B1 | A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES AND COMPOUNDS OBTAINED FROM SAID PROCESS | BOEHRINGER MANNHEIM ITALIA (IT) | 1996-10-23 | — | — | EP | claimed |
| US-5382679-A | Process for the preparation of glutathione S-acyl derivatives, compounds obtained from said process and an intermediate useful for the preparation thereof | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1995-01-17 | — | — | US | claimed |
| EP-0536231-A1 | A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES, COMPOUNDS OBTAINED FROM SAID PROCESS AND AN INTERMEDIATE USEFUL FOR THE PREPARATION THEREOF. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | claimed |
| WO-1992000320-A1 | A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES, COMPOUNDS OBTAINED FROM SAID PROCESS AND AN INTERMEDIATE USEFUL FOR THE PREPARATION THEREOF | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-01-09 | — | — | WO | claimed |