Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 10/20 | 0.55 |
| ▸ | GAA | P10253 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 12/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007939 | 1.00 | HSP90AA1 (0.57) | HSP90AA1RAB9AGAAMEN1KMT2A | |
| SCHEMBL14129429 | 0.88 | MAPT (0.52) | HSP90AA1RAB9AGAAMEN1KMT2A | |
| SCHEMBL21097694 | 0.83 | HSP90AA1 (0.55) | HSP90AA1RAB9AGAAMEN1KMT2A | |
| SCHEMBL11332710 | 0.83 | HSP90AA1 (0.55) | HSP90AA1RAB9AGAAMEN1KMT2A | |
| SCHEMBL11327597 | 0.83 | HSP90AA1 (0.55) | HSP90AA1RAB9AGAAMEN1KMT2A | |
| SCHEMBL15730811 | 0.82 | HSP90AA1 (0.50) | HSP90AA1RAB9AGAAMEN1KMT2A | |
| SCHEMBL11316602 | 0.82 | RAB9A (0.50) | HSP90AA1RAB9AGAAMEN1KMT2A | |
| SCHEMBL13209095 | 0.80 | HSP90AA1 (0.69) | HSP90AA1RAB9AGAAMEN1KMT2A | |
| SCHEMBL19119039 | 0.79 | CSNK1D (0.46) | HSP90AA1RAB9AGAAMEN1KMT2A | |
| SCHEMBL9007956 | 0.77 | MAPT (0.73) | HSP90AA1RAB9AGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476457-B1 | 2-Benzothiazolyl tetrazolium salt indicators | BAYER AG (US) | 1996-12-04 | — | — | EP | disclosed |
| EP-0476454-B1 | Analytical method using tetrazolium salt indicators having a reflectance plateau | BAYER AG (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5300637-A | Useful in determination of reducing substances | MILES INC. (US) | 1994-04-05 | — | — | US | disclosed |
| US-5126275-A | Chromogenic reducing indicators for reducing substances such as NADH | MILES INC. (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0476454-A1 | Analytical method using tetrazolium salt indicators having a reflectance plateau | Bayer Corporation (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476457-A2 | 2-Benzothiazolyl tetrazolium salt indicators | Bayer Corporation (US) | 1992-03-25 | — | — | EP | disclosed |