Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 11/20 | 0.47 |
| ▸ | NPC1 | O15118 | 10/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | INSR | P06213 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.42 |
| ▸ | RELA | Q04206 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327606 | 0.83 | MAPT (0.52) | MAPTMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL11332706 | 0.83 | MAPT (0.52) | MAPTMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL11316600 | 0.81 | MAPT (0.51) | MAPTMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL11316594 | 0.81 | MAPT (0.51) | MAPTMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL8767775 | 0.80 | NPC1 (0.54) | MAPTMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL9007939 | 0.77 | HSP90AA1 (0.57) | MAPTMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL9007943 | 0.77 | HSP90AA1 (0.57) | MAPTMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL11514759 | 0.75 | MAPT (0.46) | MAPTMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL11514766 | 0.75 | MAPT (0.46) | MAPTMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL31314986 | 0.74 | INSR (0.65) | MAPTMAPK1TDP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476457-B1 | 2-Benzothiazolyl tetrazolium salt indicators | BAYER AG (US) | 1996-12-04 | — | — | EP | disclosed |
| EP-0476454-B1 | Analytical method using tetrazolium salt indicators having a reflectance plateau | BAYER AG (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5300637-A | Useful in determination of reducing substances | MILES INC. (US) | 1994-04-05 | — | — | US | disclosed |
| US-5126275-A | Chromogenic reducing indicators for reducing substances such as NADH | MILES INC. (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0476454-A1 | Analytical method using tetrazolium salt indicators having a reflectance plateau | Bayer Corporation (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476457-A2 | 2-Benzothiazolyl tetrazolium salt indicators | Bayer Corporation (US) | 1992-03-25 | — | — | EP | disclosed |