Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL691010 | 0.91 | — | — | |
| Bicarbonate SCHEMBL166967 | 0.80 | — | — | |
| Bicarbonate SCHEMBL177966 | 0.80 | CA1 (0.71) | CA1CA2CA9LMNA | |
| Bicarbonate SCHEMBL1022672 | 0.80 | CA1 (0.71) | CA1CA2CA9LMNA | |
| Bicarbonate SCHEMBL3974066 | 0.80 | CA1 (0.71) | CA1CA2CA9LMNA | |
| Bicarbonate SCHEMBL20650 | 0.80 | — | — | |
| Bicarbonate SCHEMBL968687 | 0.80 | CA1 (0.71) | CA1CA2CA9LMNA | |
| Bicarbonate SCHEMBL6065486 | 0.80 | CA1 (0.71) | CA1CA2CA9LMNA | |
| Bicarbonate SCHEMBL10831385 | 0.80 | CA1 (0.71) | CA1CA2CA9LMNA | |
| Bicarbonate SCHEMBL4649251 | 0.80 | CA1 (0.71) | CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548338-B1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES | ANTIBIOTICOS SPA (IT) | 1996-10-23 | — | — | EP | disclosed |
| EP-0548338-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES. | ANTIBIOTICOS SPA (IT) | 1993-06-30 | — | — | EP | disclosed |
| WO-1993002085-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES | ANTIBIOTICOS S.P.A. (IT) | 1993-02-04 | — | — | WO | disclosed |