Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953847 | 0.83 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL29511002 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL384312 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL29349558 | 0.77 | ALDH1A1 (0.69) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL10870928 | 0.77 | TDP1 (0.61) | ALDH1A1TSHRTDP1CYP3A4HSD17B10 | |
| Methylamine SCHEMBL11819150 | 0.77 | ALDH1A1 (0.91) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL2146601 | 0.77 | GPR35 (0.59) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL4400528 | 0.77 | TSHR (0.69) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL48806 | 0.77 | ALDH1A1 (0.69) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL16961844 | 0.76 | HTT (0.48) | ALDH1A1TSHRTDP1CYP3A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511917-B1 | Glycosylated prodrugs, process for their preparation and uses thereof | HOECHST SA LAB (FR) | 1996-10-23 | — | — | EP | claimed |
| WO-1992019639-A1 | GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE | LABORATOIRES HOECHST (FR) | 1992-11-12 | — | — | WO | claimed |
| EP-0511917-A1 | Glycosylated prodrugs, process for their preparation and uses thereof | LABORATOIRES HOECHST S.A. (FR) | 1992-11-04 | — | — | EP | claimed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| EP-0511917-B1 | Glycosylated prodrugs, process for their preparation and uses thereof | HOECHST SA LAB (FR) | 1996-10-23 | — | — | EP | disclosed |
| WO-1992019639-A1 | GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE | LABORATOIRES HOECHST (FR) | 1992-11-12 | — | — | WO | disclosed |
| EP-0511917-A1 | Glycosylated prodrugs, process for their preparation and uses thereof | LABORATOIRES HOECHST S.A. (FR) | 1992-11-04 | — | — | EP | disclosed |
| US-4029490-A | BENZYLTHIOLCARBAMATE | ISHIHARA SANGYO KAISHA LTD. (JA) | 1977-06-14 | — | — | US | disclosed |