⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626713 | 0.79 | L3MBTL1 (0.35) | — | |
| SCHEMBL11399054 | 0.78 | L3MBTL1 (0.31) | — | |
| SCHEMBL11388024 | 0.76 | — | — | |
| SCHEMBL11398944 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL11180451 | 0.64 | — | — | |
| SCHEMBL333208 | 0.61 | — | — | |
| SCHEMBL2821117 | 0.57 | KDM4E (0.68) | — | |
| SCHEMBL458012 | 0.57 | KDM4E (0.68) | — | |
| SCHEMBL5307853 | 0.57 | — | — | |
| SCHEMBL3624681 | 0.57 | KDM4E (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548338-B1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES | ANTIBIOTICOS SPA (IT) | 1996-10-23 | — | — | EP | claimed |
| US-5387679-A | Useful intermediates in synthesis of Cefazolin and Cefazedone | ANTIBIOTICOS S.P.A. (IT) | 1995-02-07 | — | — | US | claimed |
| EP-0548338-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES. | ANTIBIOTICOS SPA (IT) | 1993-06-30 | — | — | EP | claimed |
| WO-1993002085-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES | ANTIBIOTICOS S.P.A. (IT) | 1993-02-04 | — | — | WO | claimed |
| US-4385178-A | REACTION OF A CEPHALOSPORANIC ACID WITH A THIOL COMPOUND IN THE PRESENCE OF BORON TRIFLUORIDE | TOYAMA CHEMICAL CO., LTD. (JP) | 1983-05-24 | — | — | US | claimed |
| US-4317907-A | ANHYDROUS CONDITIONS IN THE PRESENCE OF BOREN TRIFLUORIDE OR ONE OF ITS COMPLEXES | TOYAMA CHEMICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | claimed |
| US-5387679-A | Useful intermediates in synthesis of Cefazolin and Cefazedone | ANTIBIOTICOS S.P.A. (IT) | 1995-02-07 | — | — | US | disclosed |
| US-4729990-A | PENICILLIN | FARMITALIA CARLO ERBA S.P.A. (IT) | 1988-03-08 | — | — | US | disclosed |
| US-4577016-A | DISPLACEMENT | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-03-18 | — | — | US | disclosed |
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |
| US-4286089-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |
| US-4220644-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |
| US-4198406-A | Carbamoyl heterocyclicthio cephalosporins and pharmaceutical compositions formulated therewith | BEECHAM GROUP LIMITED (GB) | 1980-04-15 | — | — | US | disclosed |
| EP-0002774-A1 | Process for acylating 7aminocephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |
| US-4012379-A | 7-Acetoacetamidocephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-03-15 | — | — | US | disclosed |