Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 16/20 | 0.52 |
| ▸ | PPARA | Q07869 | 14/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879558 | 0.83 | KDM4E (0.56) | KDM4EPPARGPPARAHPGDPPARD | |
| SCHEMBL4034559 | 0.82 | KDM4E (0.73) | KDM4EPPARGPPARAHPGDPPARD | |
| SCHEMBL9520604 | 0.80 | KDM4E (0.53) | KDM4EPPARGPPARAHPGDPPARD | |
| SCHEMBL14373654 | 0.80 | KDM4E (0.59) | KDM4EPPARGPPARAHPGDPPARD | |
| SCHEMBL4031089 | 0.79 | KDM4E (0.65) | KDM4EPPARGPPARAHPGDPPARD | |
| SCHEMBL13960286 | 0.77 | KDM4E (0.55) | KDM4EPPARGPPARAPPARDFFAR1 | |
| SCHEMBL5856050 | 0.77 | KDM4E (0.62) | KDM4EPPARGPPARAHPGDPPARD | |
| SCHEMBL9128417 | 0.76 | FFAR1 (0.67) | KDM4EPPARGPPARAHPGDFFAR1 | |
| SCHEMBL5795341 | 0.76 | KDM4E (0.54) | KDM4EPPARGPPARAHPGDPPARD | |
| SCHEMBL13721668 | 0.76 | KDM4E (0.60) | KDM4EPPARGPPARAHPGDPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512689-A | TREATING A STARTING KETONE WITH A BORANE REDUCING AGENT IN THE PRESENCE OF A CHIRAL OXAZABOROLIDINE CATLAYST, PRODUCT FREE OF ENANTIMERS | PFIZER INC. (US) | 1996-04-30 | — | — | US | disclosed |