Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008215 | 0.76 | SOAT1 (0.41) | SOAT1 | |
| SCHEMBL9008269 | 0.76 | SOAT1 (0.39) | SOAT1 | |
| SCHEMBL9008076 | 0.74 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL13716589 | 0.74 | SOAT1 (0.37) | SOAT1CYP1A2 | |
| SCHEMBL9008152 | 0.74 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL9008090 | 0.73 | SOAT1 (0.35) | SOAT1 | |
| SCHEMBL9008067 | 0.73 | SOAT1 (0.35) | SOAT1 | |
| SCHEMBL9008139 | 0.73 | SOAT1 (0.35) | SOAT1 | |
| SCHEMBL32667998 | 0.73 | CYP1A2 (0.50) | SOAT1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL13716530 | 0.72 | SOAT1 (0.36) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491152-A | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |