Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008115 | 0.76 | SOAT1 (0.39) | SOAT1 | |
| SCHEMBL9008269 | 0.71 | SOAT1 (0.39) | SOAT1 | |
| SCHEMBL9000682 | 0.71 | SOAT1 (0.40) | SOAT1ALDH1A1 | |
| SCHEMBL9000628 | 0.69 | SOAT1 (0.45) | SOAT1MAPTHSD17B10LMNARXFP1 | |
| SCHEMBL9008076 | 0.69 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL13716589 | 0.69 | SOAT1 (0.37) | SOAT1ALDH1A1 | |
| SCHEMBL6284260 | 0.69 | ALDH1A1 (0.46) | SOAT1MAPTALDH1A1HSD17B10HTT | |
| SCHEMBL9008152 | 0.69 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL9008139 | 0.68 | SOAT1 (0.35) | SOAT1 | |
| SCHEMBL9008067 | 0.68 | SOAT1 (0.35) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491152-A | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |