Acetoacetic Acid

Acetoacetic Acid

SCHEMBL9008264

CC(=O)CC(=O)O.CC(=O)CC(=O)O.CC(=O)CC(=O)OCC(O)CO

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.47
DGKA P23743 1/20 0.41
FAAH O00519 4/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ADRB2 P07550 2/20 0.33
ADRB1 P08588 2/20 0.33
ADRB3 P13945 2/20 0.33
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
CNR2 P34972 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL1560961 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL391765 0.93 KDM4E (0.53) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL10445133 0.93 KDM4E (0.53) KDM4EDUSP3MEN1KMT2ALMNA
Glycerin SCHEMBL29177525 0.91 LMNA (0.51) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL1063274 0.87 LMNA (0.50) KDM4EDUSP3MEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL2586475 0.85 LMNA (0.49) KDM4EDUSP3MEN1KMT2ALMNA
Acrylic Acid SCHEMBL28069660 0.85 LMNA (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL9110406 0.82 MGAM (0.50) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL840262 0.80 LMNA (0.55) KDM4EDUSP3MEN1KMT2ALMNA
Acetoacetic Acid SCHEMBL29155554 0.80 LMNA (0.45) KDM4ELMNAMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331095-B1 Improving stability at moderate temperatures of motor vehicle components shaped from polyvinyl chloride resin compositions WITCO CORP (US) 1996-10-09 EP disclosed
US-4950704-A DIKETONE AS HEAT STABILIZER ARGUS CHEMICAL CORPORATION (US) 1990-08-21 US disclosed
EP-0331095-A1 Improving stability at moderate temperatures of motor vehicle components shaped from polyvinyl chloride resin compositions WITCO CORPORATION (US) 1989-09-06 EP disclosed
US-4346025-A Stabilized vinyl chloride polymer comprising a phenylethylidene aryl phosphite ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-08-24 US disclosed
US-4224218-A Stabilized vinyl chloride polymer comprising a metal mono-organic phosphite ARGUS CHEMICAL CORPORATION (US) 1980-09-23 US disclosed
US-4224203-A Vinyl chloride polymer stabilizer comprising a metal organophosphonate ARGUS CHEMICAL CORPORATION (US) 1980-09-23 US disclosed
US-4188960-A Fibers filter rods and other nonwoven articles made from poly(1,2-propylene terephthalate) copolyesters of terephthalic acid, 1,2-propylene glycol and ethylene glycol EASTMAN KODAK COMPANY (US) 1980-02-19 US disclosed
US-4181640-A Fibers, filter rods and other nonwoven articles made from poly(1,2-propylene terephthalate) copolyesters of terephthalic acid, 1,2-propylene glycol and ethylene glycol EASTMAN KODAK COMPANY (US) 1980-01-01 US disclosed
US-4145518-A CIGARETTES EASTMAN KODAK COMPANY (US) 1979-03-20 US disclosed
US-4134868-A Aromatic carboxylic acid ester stabilizers for PVC resins ARGUS CHEMICAL CORPORATION (US) 1979-01-16 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed