Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445133 | 1.00 | KDM4E (0.53) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL29177525 | 0.98 | LMNA (0.51) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Acetoacetic Acid SCHEMBL9008264 | 0.93 | KDM4E (0.47) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Acetoacetic Acid SCHEMBL1560961 | 0.93 | KDM4E (0.47) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL9110406 | 0.89 | MGAM (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Acrylic Acid SCHEMBL28069660 | 0.88 | LMNA (0.44) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL840262 | 0.87 | LMNA (0.55) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL16167891 | 0.84 | MEN1 (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL12199637 | 0.83 | LMNA (0.53) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL16350387 | 0.83 | MGAM (0.44) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008015-B | Process for the preparation of polyhydric alcohol esters of hydroxycarboxylic acids, in particular polyglycerol esters | 凯托利皮克斯治疗有限责任公司 | 2024-02-20 | — | — | CN | claimed |
| US-11890264-B2 | Migraine prevention and treatment | UNIVERSITATS-KINDERSPITAL BEIDER BASEL (CH) | 2024-02-06 | — | — | US | claimed |
| CN-113966323-B | Method for producing ketocarboxylic acid polyol-based esters | 凯托利皮克斯治疗有限责任公司 | 2023-11-28 | — | — | CN | claimed |
| EP-3558280-B1 | MIGRAINE PREVENTION AND TREATMENT | UNIV KINDERSPITAL BEIDER BASEL (CH) | 2023-06-07 | — | — | EP | claimed |
| CN-110087642-B | Prevention and treatment of migraine | 贝德尔巴塞尔大学儿童医院 | 2022-12-27 | — | — | CN | claimed |
| CN-114008015-A | Process for preparing polyol esters of hydroxycarboxylic acids, in particular polyglycerol esters | IOI油脂化学品有限责任公司 | 2022-02-01 | — | — | CN | claimed |
| CN-113966323-A | Method for producing ketocarboxylic acid polyol ester | IOI油脂化学品有限责任公司 | 2022-01-21 | — | — | CN | claimed |
| US-20210338618-A1 | MIGRAINE PREVENTION AND TREATMENT | UNIVERSITATS-KINDERSPITAL BEIDER BASEL (CH) | 2021-11-04 | — | — | US | claimed |
| CN-111148512-A | Delivery pharmaceutical composition comprising a penetration enhancer | 阿奎斯蒂弗医疗股份有限公司 | 2020-05-12 | — | — | CN | claimed |
| CN-110087642-A | The prevention and treatment of migraine | 贝德尔巴塞尔大学儿童医院 | 2019-08-02 | — | — | CN | claimed |
| US-20110178032-A1 | Monoglyceride of Acetoacetate and Derivatives for the Treatment of Neurological Disorders | ACCERA, INC. (US) | 2011-07-21 | — | — | US | claimed |
| EP-2303036-A1 | MONOGLYCERIDE OF ACETOACETATE AND DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Accera, Inc. (US) | 2011-04-06 | — | — | EP | claimed |
| WO-2010003114-A1 | MONOGLYCERIDE OF ACETOACETATE AND DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | NEUERA PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | claimed |
| US-5519161-A | Nutritive glycerol esters of β-acyloxy butyrates | BIRKHAHN RONALD H (US) | 1996-05-21 | — | — | US | claimed |
| WO-1995009145-A1 | NUTRITIVE GLYCEROL ESTERS OF β-ACYLOXY BUTYRATES | EASTMAN CHEMICAL COMPANY (US) | 1995-04-06 | — | — | WO | claimed |
| WO-1995009144-A1 | NUTRITIVE WATER SOLUBLE GLYCEROL ESTERS OF HYDROXY BUTYRIC ACID | EASTMAN CHEMICAL COMPANY (US) | 1995-04-06 | — | — | WO | claimed |
| EP-0348664-A2 | Pharmaceutical compositions containing monoacetoacetins for treating tumours | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-01-03 | — | — | EP | claimed |
| US-4701443-A | PARENTAL ADMINISTERING | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1987-10-20 | — | — | US | claimed |
| EP-0139677-A1 | NUTRIENT POLYESTERS | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1985-05-08 | — | — | EP | claimed |
| WO-1984003626-A1 | NUTRIENT POLYESTERS | BAXTER TRAVENOL LAB (US) | 1984-09-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178032-A1 | Monoglyceride of Acetoacetate and Derivatives for the Treatment of Neurological Disorders | FAHD1, ACAT1, ACADM | KDM4E 3010/4885DUSP3 3904/4885MEN1 1615/4885 |
| US-20210338618-A1 | MIGRAINE PREVENTION AND TREATMENT | ACACA, ACACB, HBB | KDM4E 2872/4885DUSP3 2924/4885MEN1 572/4885 |
| US-11890264-B2 | Migraine prevention and treatment | ACACA, ACACB, HBB | KDM4E 2872/4885DUSP3 2924/4885MEN1 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.