Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018251 | 1.00 | GRIA2 (0.39) | GRIA2GRIA1GRIA3MEN1MAPK1 | |
| SCHEMBL8018249 | 1.00 | GRIA2 (0.39) | GRIA2GRIA1GRIA3MEN1MAPK1 | |
| SCHEMBL8018246 | 1.00 | GRIA2 (0.39) | GRIA2GRIA1GRIA3MEN1MAPK1 | |
| SCHEMBL7767225 | 0.91 | GRIA1 (0.40) | GRIA2GRIA1GRIA3MEN1MAPK1 | |
| SCHEMBL8415930 | 0.88 | GRIA1 (0.39) | GRIA2GRIA1GRIA3MEN1MAPK1 | |
| SCHEMBL8415928 | 0.88 | GRIA1 (0.39) | GRIA2GRIA1GRIA3MEN1MAPK1 | |
| SCHEMBL20343290 | 0.84 | MEN1 (0.52) | GRIA2GRIA1GRIA3MEN1MAPK1 | |
| SCHEMBL6462690 | 0.84 | MEN1 (0.52) | GRIA2GRIA1GRIA3MEN1MAPK1 | |
| SCHEMBL6462682 | 0.84 | MEN1 (0.52) | GRIA2GRIA1GRIA3MEN1MAPK1 | |
| SCHEMBL9008539 | 0.84 | DRD2 (0.43) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |