Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026759 | 0.87 | KDM4E (0.62) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7432913 | 0.87 | CYP2C9 (0.64) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9452427 | 0.83 | CACNA1C (0.70) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9452424 | 0.83 | CACNA1C (0.70) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7370479 | 0.82 | TBXA2R (0.52) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11183512 | 0.81 | ALDH1A1 (0.51) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7380877 | 0.81 | KDM4E (0.54) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3035724 | 0.81 | KDM4E (0.68) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29676073 | 0.81 | KDM4E (0.68) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7370944 | 0.81 | TBXA2R (0.51) | CACNA1BCYP2C9CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552379-B1 | DIHYDROPYRIDINE DERIVATIVES, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-30 | — | — | EP | disclosed |
| EP-0552379-A1 | DIHYDROPYRIDINE DERIVATIVES, AND PROCESS FOR THEIR PREPARATION. | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-07-28 | — | — | EP | disclosed |