SCHEMBL9008636

SCHEMBL9008636

CO/N=C(\C(=O)OC)c1ccccc1/C=N/OC(=O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.43
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
PLA2G7 Q13093 3/20 0.37
MAPT P10636 1/20 0.36
NPC1 O15118 1/20 0.36
CRHBP P24387 1/20 0.36
RAB9A P51151 1/20 0.36
CRHR2 Q13324 1/20 0.36
POLB P06746 1/20 0.35
CYP2C19 P33261 1/20 0.35
TNF P01375 1/20 0.35
KLF5 Q13887 1/20 0.35
NOD1 Q9Y239 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9008638 1.00 HIF1A (0.43) HIF1AHTTLMNACYP1A2CYP2D6
SCHEMBL9258272 0.82 HIF1A (0.49) HIF1ALMNANPC1RAB9ASMN1; SMN2
SCHEMBL9258268 0.82 HIF1A (0.49) HIF1ALMNANPC1RAB9ASMN1; SMN2
SCHEMBL8760949 0.76 HIF1A (0.54) HIF1AHTTLMNAMAPTPOLB
SCHEMBL8760953 0.76 HIF1A (0.54) HIF1AHTTLMNAMAPTPOLB
SCHEMBL8026715 0.75 HIF1A (0.47) HIF1AHTTLMNAMAPTPOLB
SCHEMBL7210367 0.74 HIF1A (0.46) HIF1AHTTLMNA
SCHEMBL7210372 0.74 HIF1A (0.46) HIF1AHTTLMNA
SCHEMBL7463069 0.74 HIF1A (0.46) HIF1AHTTLMNA
SCHEMBL7141540 0.72 MAOB (0.53) HIF1ALMNAMAPTSMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738708-A1 Methoxyiminoacetic acid derivative and agricultural/horticultural fungicide containing the same as active ingredient Mitsubishi Chemical Corporation (JP) 1996-10-23 EP disclosed
EP-0596254-A1 Methoxyiminoacetic acid derivative and agricultural/horticultural fungicide containing the same as active ingredient Mitsubishi Chemical Corporation (JP) 1994-05-11 EP disclosed