Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.81 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.81 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.81 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.81 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.81 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.81 |
| ▸ | HRH1 | P35367 | 1/20 | 0.81 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.81 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.81 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.81 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.81 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107439 | 1.00 | ADRA1A (0.81) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 | |
| SCHEMBL9107533 | 1.00 | ADRA1A (0.81) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 | |
| SCHEMBL9008606 | 1.00 | ADRA1A (0.81) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 | |
| SCHEMBL9008867 | 1.00 | ADRA1A (0.81) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 | |
| SCHEMBL9108716 | 1.00 | ADRA1A (0.81) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 | |
| Terodiline SCHEMBL78908 | 0.90 | HRH1 (1.00) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 | |
| Terodiline SCHEMBL9008621 | 0.90 | HRH1 (1.00) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 | |
| Terodiline SCHEMBL579993 | 0.88 | HRH1 (0.96) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 | |
| Terodiline SCHEMBL121864 | 0.88 | HRH1 (0.96) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 | |
| Terodiline SCHEMBL110026 | 0.86 | HRH1 (0.93) | ADRA1ASLC6A3KCNH2ADRA2BOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492933-A | SIDE EFFECT REDUCTION | SEPRACOR, INC. (US) | 1996-02-20 | — | — | US | disclosed |