Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TK1 | P04183 | 8/20 | 0.50 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | POLD1 | P28340 | 1/20 | 0.46 |
| ▸ | TK2 | O00142 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008931 | 1.00 | POLB (0.51) | POLBTK1POLA1POLD1TK2 | |
| SCHEMBL6910401 | 0.80 | POLB (0.54) | POLBTK1POLA1POLD1 | |
| SCHEMBL10684890 | 0.80 | POLB (0.54) | POLBTK1POLA1POLD1 | |
| SCHEMBL7201324 | 0.78 | TK1 (0.60) | POLBTK1 | |
| SCHEMBL9008859 | 0.78 | POLG (0.51) | POLB | |
| SCHEMBL9008942 | 0.78 | POLG (0.51) | POLB | |
| SCHEMBL5358020 | 0.77 | TK2 (0.55) | TK1TK2 | |
| SCHEMBL5372684 | 0.77 | TK2 (0.55) | TK1TK2 | |
| SCHEMBL7525577 | 0.77 | TK1 (0.61) | POLBTK1 | |
| SCHEMBL27984187 | 0.77 | TK1 (0.61) | POLBTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738274-A1 | NOVEL NUCLEOSIDE-LIPID ADDITION COMPOUNDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 1996-10-23 | — | — | EP | claimed |
| WO-1995018816-A1 | NOVEL NUCLEOSIDE-LIPID ADDITION COMPOUNDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 1995-07-13 | — | — | WO | claimed |
| EP-0738274-A1 | NOVEL NUCLEOSIDE-LIPID ADDITION COMPOUNDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 1996-10-23 | — | — | EP | disclosed |
| WO-1995018816-A1 | NOVEL NUCLEOSIDE-LIPID ADDITION COMPOUNDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 1995-07-13 | — | — | WO | disclosed |