Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TK1 | P04183 | 7/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
| ▸ | POLD1 | P28340 | 1/20 | 0.53 |
| ▸ | DTYMK | P23919 | 2/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684890 | 0.89 | POLB (0.54) | POLBTK1POLA1POLD1DTYMK | |
| SCHEMBL2379396 | 0.83 | POLB (0.56) | POLBTK1POLA1POLD1 | |
| SCHEMBL25700727 | 0.81 | TK1 (0.60) | POLBTK1TYMS | |
| SCHEMBL25756099 | 0.81 | TK1 (0.60) | POLBTK1TYMS | |
| SCHEMBL25752637 | 0.81 | TK1 (0.60) | POLBTK1TYMS | |
| SCHEMBL7201324 | 0.81 | TK1 (0.60) | POLBTK1TYMS | |
| SCHEMBL316663 | 0.80 | TK1 (0.65) | POLBTK1 | |
| SCHEMBL9008929 | 0.80 | POLB (0.51) | POLBTK1POLA1POLD1 | |
| SCHEMBL9008931 | 0.80 | POLB (0.51) | POLBTK1POLA1POLD1 | |
| SCHEMBL7525577 | 0.80 | TK1 (0.61) | POLBTK1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084266-B1 | THE APPLICATION OF 5'-MODIFIED NUCLEOTIDES IN MOLECULAR BIOLOGY AND MEDICINE | EUROP LAB MOLEKULARBIOLOG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6627416-B1 | Synthesizing copies of double-stranded nucleic acid from a single-stranded one by enzymatic incorporation of compound of given formula; site-directed cleavage; use for detecting nucleic acids and mutations and for sequencing | EUROPAISCHES LABORATORIUM FUR MOLEKULARBIOLOGIE (EMBL) (DE) | 2003-09-30 | — | — | US | disclosed |
| EP-1084266-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (DE) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999053087-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (EMBL) (DE) | 1999-10-21 | — | — | WO | disclosed |