Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008915 | 0.91 | SCN9A (0.39) | TRPV3MEN1RAB9AKMT2AHCRTR1 | |
| SCHEMBL9174404 | 0.82 | SMN1; SMN2 (0.42) | MEN1RAB9AKMT2AKCNH2SMN1; SMN2 | |
| SCHEMBL8777276 | 0.81 | KCNH2 (0.41) | TRPV3KCNH2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL4134240 | 0.81 | KCNH2 (0.38) | KCNH2HTR7CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL4136544 | 0.79 | GRM5 (0.38) | PDE10AKCNH2HTR1ADRD2HTR2A | |
| SCHEMBL7467379 | 0.77 | MRGPRX4 (0.49) | — | |
| SCHEMBL8777267 | 0.77 | KCNH2 (0.35) | KCNH2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL13831044 | 0.76 | MEN1 (0.54) | TRPV3MEN1RAB9AKMT2APDE10A | |
| SCHEMBL2225215 | 0.74 | POLB (0.38) | MEN1KMT2A | |
| SCHEMBL8977847 | 0.74 | MRGPRX4 (0.47) | RAB9ACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576338-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS AND CYTOPROTECTIVE AGENTS FOR CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1996-11-19 | — | — | US | disclosed |