Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777276 | 0.83 | KCNH2 (0.41) | SMN1; SMN2KCNH2CCR1LMNA | |
| SCHEMBL4134240 | 0.83 | KCNH2 (0.38) | SMN1; SMN2KCNH2KDM1AMAOAMAOB | |
| SCHEMBL9008955 | 0.82 | TRPV3 (0.43) | SMN1; SMN2MEN1KMT2AKCNH2RAB9A | |
| SCHEMBL7467379 | 0.80 | MRGPRX4 (0.49) | — | |
| SCHEMBL8777267 | 0.80 | KCNH2 (0.35) | SMN1; SMN2KCNH2 | |
| SCHEMBL4136544 | 0.79 | GRM5 (0.38) | SMN1; SMN2KCNH2GABRA1GABRG2GABRB3 | |
| SCHEMBL20983501 | 0.78 | CYP3A4 (0.33) | SMN1; SMN2 | |
| SCHEMBL15968790 | 0.77 | MEN1 (0.39) | SMN1; SMN2MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL30505267 | 0.77 | MEN1 (0.39) | SMN1; SMN2MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL9008915 | 0.76 | SCN9A (0.39) | MEN1KMT2ANPC1RAB9ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656896-A1 | NEW LEUKOTRIENE-B4 ANTAGONISTS, PROCESS FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-14 | — | — | EP | disclosed |
| WO-1994004522-A1 | NEW LEUKOTRIENE-B4 ANTAGONISTS, PROCESS FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-03-03 | — | — | WO | disclosed |