Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160636 | 0.81 | MEN1 (0.59) | SMN1; SMN2FFAR1GSTP1MEN1KMT2A | |
| SCHEMBL5042093 | 0.81 | ALOX5 (0.55) | SMN1; SMN2FFAR1GSTP1CYP19A1MEN1 | |
| SCHEMBL1956583 | 0.80 | MRGPRX4 (0.58) | PDE4BROCK2GRK2 | |
| SCHEMBL1957932 | 0.79 | F2 (0.62) | F2KCNH2GRIN2BSMN1; SMN2FFAR1 | |
| Tert-Butyl Formate SCHEMBL27828076 | 0.76 | GSTP1 (0.43) | FFAR1GSTP1CYP19A1MEN1KMT2A | |
| SCHEMBL953509 | 0.75 | F2 (0.65) | F2KCNH2GRIN2BSMN1; SMN2ALOX5 | |
| SCHEMBL16886123 | 0.74 | CYP1A2 (0.58) | FFAR1CYP19A1MEN1KMT2AALOX5 | |
| SCHEMBL31183087 | 0.74 | CYP1A2 (0.58) | FFAR1CYP19A1MEN1KMT2AALOX5 | |
| SCHEMBL17137714 | 0.74 | IP6K1 (0.44) | FFAR1GSTP1PRMT5 | |
| SCHEMBL3565011 | 0.73 | LTB4R (0.53) | FFAR1GSTP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576338-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS AND CYTOPROTECTIVE AGENTS FOR CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1996-11-19 | — | — | US | disclosed |