Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030922 | 0.90 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3718498 | 0.89 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9352754 | 0.89 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL7995861 | 0.88 | LMNA (0.55) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL12871731 | 0.87 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL5028753 | 0.87 | LMNA (0.57) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL13220211 | 0.87 | LMNA (0.57) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL10624509 | 0.87 | LMNA (0.57) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8375505 | 0.87 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8378687 | 0.87 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646021-B1 | PURIFICATION OF CRUDE IOVERSOL USING CONTINUOUS DEIONIZATION | MALLINCKRODT MEDICAL INC (US) | 1996-11-27 | — | — | EP | claimed |
| EP-0083964-B1 | COMPOUNDS SUITABLE FOR X-RAY VISUALISATION METHODS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1986-04-16 | — | — | EP | claimed |
| EP-0571593-B1 | NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM | INVEST JUSTESA IMAGEN S A CENT (ES) | 1996-10-30 | — | — | EP | disclosed |
| US-5403576-A | Iodo-phenylated chelates for magnetic resonance imaging | MALLINCKRODT MEDICAL, INC. (US) | 1995-04-04 | — | — | US | disclosed |
| EP-0625263-A1 | CONTRAST AGENTS USEFUL FOR BOTH X-RAY AND MRI | MALLINCKRODT MEDICAL, INC. (US) | 1994-11-23 | — | — | EP | disclosed |
| US-5324503-A | Iodo-phenylated chelates for x-ray contrast | MALLINCKRODT MEDICAL, INC. (US) | 1994-06-28 | — | — | US | disclosed |
| WO-1993016375-A1 | CONTRAST AGENTS USEFUL FOR BOTH X-RAY AND MRI | MALLINCKRODT MEDICAL, INC. (US) | 1993-08-19 | — | — | WO | disclosed |