SCHEMBL5028753

SCHEMBL5028753

O=C(CCl)Nc1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
CYP2C19 P33261 1/20 0.51
HIF1A Q16665 1/20 0.51
EGFR P00533 1/20 0.35
SRC P12931 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
MAP2K1 Q02750 7/20 0.34
MAP2K2 P36507 2/20 0.33
PRKCZ Q05513 1/20 0.33
IARS2 Q9NSE4 1/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
S1PR4 O95977 1/20 0.32
S1PR1 P21453 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052588 0.95 LMNA (0.53) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL5030922 0.89 LMNA (0.60) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL9352754 0.87 LMNA (0.58) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL9009053 0.87 LMNA (0.58) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL12871731 0.86 LMNA (0.60) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL13220211 0.86 LMNA (0.57) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL14087101 0.86 LMNA (0.51) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL10624509 0.86 LMNA (0.57) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL8378687 0.85 LMNA (0.56) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL3062459 0.85 LMNA (0.54) LMNACYP2C19HIF1AEGFRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116421744-A Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2023-07-14 CN claimed
WO-2008104853-A1 PROCESSES FOR THE PREPARATION OF PURE IOVERSOL WOCKHARDT RESEARCH CENTRE (IN) 2008-09-04 WO claimed
US-6596904-B1 Process for producing ioversol MALLINC KRODT INC 2003-07-22 US claimed
EP-0839056-B1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT INC (US) 2003-05-07 EP claimed
EP-0886634-B1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT INC (US) 2002-04-24 EP claimed
US-5648536-A Process for producing ioversol LAFAYETTE PHARMACEUTICALS LLC 1997-07-15 US claimed
CN-115093342-B Industrial production method of ioversol 安徽普利药业有限公司 2025-03-07 CN disclosed
CN-117800986-A Preparation method of ioversol impurity 重庆圣华曦药业股份有限公司 2024-04-02 CN disclosed
CN-116421744-B Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2024-02-09 CN disclosed
CN-116768747-A Intermediate of ioversol and method for preparing ioversol 江苏宇田医药有限公司 2023-09-19 CN disclosed
CN-116421744-A Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2023-07-14 CN disclosed
CN-115806500-A Synthesis of ioversol polysubstituent 大道隆达(北京)医药科技发展有限公司 2023-03-17 CN disclosed
CN-115093342-A Industrial production method of ioversol 安徽普利药业有限公司 2022-09-23 CN disclosed
EP-0839056-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1998-05-06 EP disclosed
WO-1997027172-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1997-07-31 WO disclosed
US-5648536-A Process for producing ioversol LAFAYETTE PHARMACEUTICALS LLC 1997-07-15 US disclosed
US-5648536-A Process for producing ioversol LAFAYETTE PHARMACEUTICALS LLC 1997-07-15 US disclosed
WO-1996040286-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1996-12-19 WO disclosed
WO-1996040286-A1 PROCESS FOR PRODUCING IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1996-12-19 WO disclosed
EP-0571593-B1 NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM INVEST JUSTESA IMAGEN S A CENT (ES) 1996-10-30 EP disclosed