Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iomeprol SCHEMBL26981 | 0.90 | LMNA (0.63) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL15988174 | 0.88 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL363705 | 0.88 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9009051 | 0.87 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL29472329 | 0.87 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8743088 | 0.87 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8377986 | 0.87 | LMNA (0.63) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9735781 | 0.87 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL14790186 | 0.86 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9389731 | 0.86 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571593-B1 | NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM | INVEST JUSTESA IMAGEN S A CENT (ES) | 1996-10-30 | — | — | EP | disclosed |