Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7363241 | 0.91 | ITGB3 (0.66) | ITGB3ITGA2BMDM2ITGA2HDAC1 | |
| SCHEMBL9009507 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BMDM2PTGDR2ALDH1A1 | |
| SCHEMBL8837116 | 0.85 | ITGB3 (0.72) | ITGB3ITGA2BMDM2PTGDR2HDAC1 | |
| SCHEMBL7363160 | 0.81 | ITGB3 (0.61) | ITGB3ITGA2BMDM2PTGDR2KDM4E | |
| Trifluoroacetic Acid SCHEMBL8959450 | 0.80 | ITGB3 (0.66) | ITGB3ITGA2BFFAR1 | |
| Trifluoroacetic Acid SCHEMBL8959426 | 0.80 | ITGB3 (0.51) | ITGB3ITGA2BPTGDR2ITGA2HDAC1 | |
| Trifluoroacetic Acid SCHEMBL7325747 | 0.79 | ITGB3 (0.68) | ITGB3ITGA2BFFAR1KDM4EITGA2 | |
| SCHEMBL7363243 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2BALDH1A1HDAC1HDAC2 | |
| Trifluoroacetic Acid SCHEMBL7325169 | 0.78 | ITGB3 (0.73) | ITGB3ITGA2BKDM4EITGA2 | |
| Trifluoroacetic Acid SCHEMBL7325545 | 0.77 | ITGB3 (0.55) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565449-A | PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1996-10-15 | — | — | US | disclosed |