Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202245 | 0.83 | KMT2A (0.48) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL30253490 | 0.83 | KMT2A (0.48) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL29617524 | 0.83 | KMT2A (0.48) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL21838309 | 0.78 | KMT2A (0.44) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL3590981 | 0.78 | KMT2A (0.44) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL9009580 | 0.78 | P2RX4 (0.50) | KMT2A | |
| SCHEMBL13327274 | 0.75 | POLB (0.52) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL22397770 | 0.75 | POLB (0.52) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL789074 | 0.75 | FABP5 (0.48) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL29430507 | 0.75 | FABP5 (0.48) | KMT2AFABP5FABP7EPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516070-B1 | Protected tryptophan derivatives, process to synthetize them and their use | CALBIOCHEM NOVABIOCHEM AG (CH) | 1996-11-06 | — | — | EP | claimed |
| EP-0516070-A1 | Protected tryptophan derivatives, process to synthetize them and their use | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1992-12-02 | — | — | EP | claimed |
| EP-0516070-B1 | Protected tryptophan derivatives, process to synthetize them and their use | CALBIOCHEM NOVABIOCHEM AG (CH) | 1996-11-06 | — | — | EP | disclosed |
| US-5300651-A | Protected derivatives of tryptophan, processes for their preparation and their use for the preparation of dipeptide, polypeptide or protein structures | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1994-04-05 | — | — | US | disclosed |
| EP-0516070-A1 | Protected tryptophan derivatives, process to synthetize them and their use | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1992-12-02 | — | — | EP | disclosed |