SCHEMBL789074

SCHEMBL789074

O=C(OCC1c2ccccc2-c2ccccc21)C1CC(=O)N(O)C1=O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.48
FABP7 O15540 2/20 0.48
KMT2A Q03164 2/20 0.43
TSHR P16473 1/20 0.41
EPHX2 P34913 1/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
MDM4 O15151 1/20 0.35
TP53 P04637 1/20 0.35
CASP3 P42574 1/20 0.35
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29430507 1.00 FABP5 (0.48) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL3491073 0.87 FABP5 (0.39) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL4478311 0.85 FABP5 (0.36) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL30876356 0.84 FABP5 (0.46) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL622854 0.84 FABP5 (0.46) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL15789977 0.84 FABP5 (0.44) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL17941734 0.82 KMT2A (0.47) FABP5FABP7KMT2AEPHX2MDM4
SCHEMBL6206197 0.81 TSHR (0.48) TSHR
SCHEMBL5663756 0.81 FABP5 (0.43) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL3194549 0.80 POLB (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2005503256-A 2005-02-03 JP claimed
US-20040242915-A1 Modified alumina catalyst BIOCON LIMITED (IN) 2004-12-02 US claimed
EP-1427526-A1 MODIFIED ALUMINA CATALYST Biocon Limited (IN) 2004-06-16 EP claimed
WO-2003024591-A1 MODIFIED ALUMINA CATALYST BIOCON LIMITED (IN) 2003-03-27 WO claimed
US-6127129-A DEPOSITING OMEGA MODIFIED ALKANETHIOL MONOLAYER, BLOCKING WITH HYDROPHOBIC PROTECTING GROUPS, PATTERNING, DEPOSITING AGAIN IN EXPOSED AREAS, ATTACHING MOLECULES/CELLS TO THOSE SPOTS, DEBLOCKING, MAKING RESISTANT TO NON-SPECIFIC PROTEIN WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2000-10-03 US claimed
EP-0618219-A1 Procedure for obtaining carbocalcitonin LIPOTEC, S.A. (ES) 1994-10-05 EP claimed
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2026-04-16 US disclosed
US-20250237656-A1 METHOD FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE ROCHE DIAGNOSTICS OPERATIONS, INC. 2025-07-24 US disclosed
US-20250163104-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2025-05-22 US disclosed
CN-112105625-B Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same 赛诺菲 2024-12-31 CN disclosed
US-20240409585-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY 2024-12-12 US disclosed
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2024-11-14 US disclosed
EP-4441069-A1 MACROCYCLIC IMMUNOMODULATORS Bristol-Myers Squibb Company (US) 2024-10-09 EP disclosed
WO-1991019735-A1 LIBRARIES OF MODIFIED PEPTIDES WITH PROTEASE RESISTANCE BARTLETT PAUL A (US) 1991-12-26 WO disclosed
EP-0433112-A1 Modified gangliosides and the functional derivatives thereof FIDIA S.p.A. (IT) 1991-06-19 EP disclosed
EP-0431784-A2 Methods for treating retroviral infection ELI LILLY AND COMPANY (US) 1991-06-12 EP disclosed
EP-0410881-A2 Semisynthetic ganglioside analogues FIDIA S.p.A. (IT) 1991-01-30 EP disclosed
EP-0410883-A2 Di-lysogangliosides derivatives FIDIA S.p.A. (IT) 1991-01-30 EP disclosed
EP-0374097-A2 Use of peptide isosteres as retroviral protease inhibitors CIBA-GEIGY AG (CH) 1990-06-20 EP disclosed
EP-0373039-A2 New lysoganglioside derivatives FIDIA S.p.A. (IT) 1990-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163104-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 FABP5 2427/4885FABP7 2559/4885KMT2A 2735/4885
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME NSUN2, NSUN3, SNRPA FABP5 4131/4885FABP7 3185/4885KMT2A 1794/4885
US-20240409585-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 FABP5 2253/4885FABP7 2379/4885KMT2A 2325/4885
US-20040242915-A1 Modified alumina catalyst ADH1A, APEX1, AAAS FABP5 4126/4885FABP7 3632/4885KMT2A 268/4885
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME RNMT, NSUN2, ADAR FABP5 3246/4885FABP7 3421/4885KMT2A 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.