Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22175038 | 0.82 | HTR2C (0.50) | P2RX4CTRB1P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL22214513 | 0.81 | HTR2C (0.46) | P2RX4CTRB1P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL20888347 | 0.81 | CTRB1 (0.46) | P2RX4CTRB1P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL22184884 | 0.81 | HTR2C (0.55) | P2RX4CTRB1P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL22175043 | 0.80 | HTR2C (0.48) | P2RX4CTRB1P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL274967 | 0.79 | P2RX4 (0.58) | P2RX4CTRB1P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL9009565 | 0.78 | KMT2A (0.44) | KMT2A | |
| SCHEMBL24939029 | 0.77 | CTRB1 (0.47) | P2RX4CTRB1P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL24939028 | 0.77 | CTRB1 (0.47) | P2RX4CTRB1P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL876243 | 0.77 | SMN1; SMN2 (0.49) | P2RX4CTRB1P2RX1P2RX3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516070-B1 | Protected tryptophan derivatives, process to synthetize them and their use | CALBIOCHEM NOVABIOCHEM AG (CH) | 1996-11-06 | — | — | EP | disclosed |
| US-5300651-A | Protected derivatives of tryptophan, processes for their preparation and their use for the preparation of dipeptide, polypeptide or protein structures | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1994-04-05 | — | — | US | disclosed |
| EP-0516070-A1 | Protected tryptophan derivatives, process to synthetize them and their use | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1992-12-02 | — | — | EP | disclosed |