SCHEMBL900958

SCHEMBL900958

Sc1ccc(C2(c3ccc(S)cc3)CCCCC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.60
ESR2 Q92731 4/20 0.60
ALDH1A1 P00352 2/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
SLC6A4 P31645 1/20 0.55
SLC6A3 Q01959 1/20 0.55
LMNA P02545 2/20 0.43
ALOX12 P18054 2/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
PSMB1 P20618 1/20 0.41
PSMB5 P28074 1/20 0.41
PSMB2 P49721 1/20 0.41
ACHE P22303 1/20 0.39
ADORA3 P0DMS8 1/20 0.37
OPRM1 P35372 1/20 0.33
HSD11B1 P28845 1/20 0.33
HSD11B2 P80365 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14012083 0.91 ESR1 (0.52) ESR1ESR2ALDH1A1L3MBTL1SLC6A4
SCHEMBL15571977 0.89 ESR2 (0.80) ESR1ESR2ALDH1A1L3MBTL1SLC6A4
SCHEMBL11152421 0.79 ESR1 (0.65) ESR1ESR2ALDH1A1L3MBTL1SLC6A4
SCHEMBL14804301 0.75 ESR1 (0.60) ESR1ESR2ALDH1A1L3MBTL1LMNA
SCHEMBL940952 0.75 ALDH1A1 (1.00) ESR1ESR2ALDH1A1L3MBTL1LMNA
SCHEMBL23198924 0.75 ALDH1A1 (1.00) ESR1ESR2ALDH1A1L3MBTL1LMNA
SCHEMBL100902 0.75 ALDH1A1 (1.00) ESR1ESR2ALDH1A1L3MBTL1LMNA
SCHEMBL13379655 0.75 ESR2 (1.00) ESR1ESR2ALDH1A1L3MBTL1SLC6A4
SCHEMBL6205256 0.75 ESR1 (0.60) ESR1ESR2ALDH1A1L3MBTL1LMNA
SCHEMBL10777847 0.75 ESR2 (1.00) ESR1ESR2ALDH1A1L3MBTL1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
EP-3626702-B1 CARBONATE DERIVATIVE PRODUCTION METHOD UNIV KOBE NAT UNIV CORP (JP) 2023-02-15 EP disclosed
CN-110637006-B Process for producing carbonate derivative 国立大学法人神户大学 2022-05-24 CN disclosed
CN-111801388-B High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2022-04-01 CN disclosed
US-11130728-B2 Carbonate derivative production method NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2021-09-28 US disclosed
US-20210095128-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM LG CHEM, LTD. (KR) 2021-04-01 US disclosed
EP-3626702-A1 CARBONATE DERIVATIVE PRODUCTION METHOD National University Corporation Kobe University (JP) 2020-03-25 EP disclosed
US-20200079723-A1 CARBONATE DERIVATIVE PRODUCTION METHOD NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2020-03-12 US disclosed
US-20190211202-A1 ADDUCTS AND USES THEREOF HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2019-07-11 US disclosed
EP-3500627-A1 ADDUCTS AND USES THEREOF Huntsman Advanced Materials Americas LLC (US) 2019-06-26 EP disclosed
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US disclosed
US-5414121-A Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1995-05-09 US disclosed
US-5362822-A Epoxy resin for polyurethane having enhanced mechanical properties THE DOW CHEMICAL COMPANY (US) 1994-11-08 US disclosed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US disclosed
US-5276184-A Curing agents for epoxy resins for thermosetting resins THE DOW CHEMICAL COMPANY (US) 1994-01-04 US disclosed
US-5241021-A Reacting isocyanate with alkoxylated epoxy resin adducts and one or more compounds having active hydrogens; blowing agents THE DOW CHEMICAL COMPANY (US) 1993-08-31 US disclosed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US disclosed
US-5189117-A Tensile strength, tear strength, waterproofing THE DOW CHEMICAL COMPANY (US) 1993-02-23 US disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200079723-A1 CARBONATE DERIVATIVE PRODUCTION METHOD CA4, CA14, CA3 ESR1 2049/4885ESR2 1968/4885ALDH1A1 2606/4885
US-11130728-B2 Carbonate derivative production method CA4, CA14, CA3 ESR1 2049/4885ESR2 1968/4885ALDH1A1 2606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.