Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579212 | 1.00 | TSHR (0.43) | TSHRLPAR3LPAR2ALDH1A1LPAR1 | |
| SCHEMBL3902659 | 0.98 | TSHR (0.39) | TSHRLPAR3LPAR2ALDH1A1LPAR1 | |
| SCHEMBL28979497 | 0.94 | TSHR (0.39) | TSHRLPAR3LPAR2ALDH1A1LPAR1 | |
| SCHEMBL29161772 | 0.94 | TSHR (0.39) | TSHRLPAR3LPAR2ALDH1A1LPAR1 | |
| SCHEMBL27841978 | 0.94 | TSHR (0.39) | TSHRLPAR3LPAR2ALDH1A1LPAR1 | |
| SCHEMBL10845976 | 0.93 | HTT (0.41) | TSHRLPAR3LPAR2ALDH1A1THRB | |
| SCHEMBL389689 | 0.91 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL28947893 | 0.90 | TSHR (0.39) | TSHRLPAR3LPAR2ALDH1A1LPAR1 | |
| SCHEMBL10847978 | 0.89 | HTT (0.46) | TSHRLPAR3LPAR2ALDH1A1THRB | |
| SCHEMBL22654174 | 0.88 | TSHR (0.35) | TSHRLPAR3LPAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646672-B1 | Coated fabrics for air bags | WACKER CHEMIE GMBH (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0646672-A1 | Coated fabrics for air bags | Wacker-Chemie GmbH (DE) | 1995-04-05 | — | — | EP | disclosed |
| US-5401566-A | Polysiloxane coating | WACKER SILICONES CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| US-4618389-A | ALKENYLTRITHYDROCARBONOXYSILANE | SWS SILICONES CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |
| EP-0124865-A2 | A process for bonding heat curable silicone rubber to a substrate using an aqueous primer composition | Wacker Silicones Corporation (US) | 1984-11-14 | — | — | EP | disclosed |