SCHEMBL4579212

SCHEMBL4579212

C=CC[Si](OCCCCCC)(OCCCCCC)OCCCCCC

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.43
LPAR3 Q9UBY5 6/20 0.36
LPAR2 Q9HBW0 5/20 0.36
ALDH1A1 P00352 1/20 0.36
LPAR1 Q92633 3/20 0.34
THRB P10828 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
PLA2G2C Q5R387 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009705 1.00 TSHR (0.43) TSHRLPAR3LPAR2ALDH1A1LPAR1
SCHEMBL3902659 0.98 TSHR (0.39) TSHRLPAR3LPAR2ALDH1A1LPAR1
SCHEMBL28979497 0.94 TSHR (0.39) TSHRLPAR3LPAR2ALDH1A1LPAR1
SCHEMBL29161772 0.94 TSHR (0.39) TSHRLPAR3LPAR2ALDH1A1LPAR1
SCHEMBL27841978 0.94 TSHR (0.39) TSHRLPAR3LPAR2ALDH1A1LPAR1
SCHEMBL10845976 0.93 HTT (0.41) TSHRLPAR3LPAR2ALDH1A1THRB
SCHEMBL389689 0.91 TSHR (0.39) TSHRALDH1A1
SCHEMBL28947893 0.90 TSHR (0.39) TSHRLPAR3LPAR2ALDH1A1LPAR1
SCHEMBL10847978 0.89 HTT (0.46) TSHRLPAR3LPAR2ALDH1A1THRB
SCHEMBL22654174 0.88 TSHR (0.35) TSHRLPAR3LPAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120193667-A1 Method for Controlling Fluidity of Phosphor, Phosphor and Phosphor Paste SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2012-08-02 US claimed
US-20080103276-A1 Method for Controlling Fluidity of Phosphor, Phosphor and Phosphor Paste SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2008-05-01 US claimed
EP-1549657-B1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES DOW CORNING (US) 2006-06-28 EP claimed
EP-1549657-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES Dow Corning Corporation (US) 2005-07-06 EP claimed
US-6878839-B2 Method for preparing organofunctional silanes DOW CORNING CORPORATION (US) 2005-04-12 US claimed
WO-2004033469-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES DOW CORNING CORPORATION (US) 2004-04-22 WO claimed
US-20040073053-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES DOW CORNING CORPORATION 2004-04-15 US claimed
US-11028256-B2 Silica-containing rubber compositions containing specified coupling agents and related methods BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2021-06-08 US disclosed
US-20200123349-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2020-04-23 US disclosed
US-20170247532-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2017-08-31 US disclosed
EP-3197950-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS Bridgestone Americas Tire Operations, LLC (US) 2017-08-02 EP disclosed
WO-2016048935-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2016-03-31 WO disclosed
US-20120193667-A1 Method for Controlling Fluidity of Phosphor, Phosphor and Phosphor Paste SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2012-08-02 US disclosed
US-20080103276-A1 Method for Controlling Fluidity of Phosphor, Phosphor and Phosphor Paste SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2008-05-01 US disclosed
EP-1549657-B1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES DOW CORNING (US) 2006-06-28 EP disclosed
EP-1549657-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES Dow Corning Corporation (US) 2005-07-06 EP disclosed
US-6878839-B2 Method for preparing organofunctional silanes DOW CORNING CORPORATION (US) 2005-04-12 US disclosed
WO-2004033469-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES DOW CORNING CORPORATION (US) 2004-04-22 WO disclosed
US-20040073053-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES DOW CORNING CORPORATION 2004-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040073053-A1 METHOD FOR PREPARING ORGANOFUNCTIONAL SILANES MSMO1, ADH1A, ADH1C TSHR 3849/4885LPAR3 2510/4885LPAR2 2123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.