Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751788 | 0.72 | PIK3CG (0.38) | LRRK2DYRK1AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6486674 | 0.70 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL6029056 | 0.70 | SMN1; SMN2 (0.38) | TRPV4EGLN2KDM4EALDH1A1GAA | |
| SCHEMBL7608827 | 0.69 | TRPV4 (0.33) | TRPV4KDM4EALDH1A1 | |
| SCHEMBL1997754 | 0.69 | LRRK2 (0.34) | LRRK2DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL27158634 | 0.67 | SMN1; SMN2 (0.40) | KDM4EALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL2237565 | 0.67 | SMN1; SMN2 (0.36) | EGLN2KDM4EALDH1A1GAALMNA | |
| SCHEMBL20836128 | 0.67 | CYP11B2 (0.41) | LRRK2EGLN2KDM4EALDH1A1GAA | |
| SCHEMBL890661 | 0.67 | LRRK2 (0.50) | LRRK2DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL8165803 | 0.67 | TRPV4 (0.32) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502173-A | Process for the preparation of a substituted 2-amino-1-sulphonaphthalene | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| EP-0494456-A1 | Improved process for the preparation of a substituted 2-amino-1-sulfonaphthaline | BAYER AG (DE) | 1992-07-15 | — | — | EP | disclosed |
| EP-0321784-B1 | FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0203505-B1 | DISAZO METAL COMPLEX DYES | BAYER AG (DE) | 1989-05-24 | — | — | EP | disclosed |
| EP-0186812-B1 | REACTIVE DYES | BAYER AG (DE) | 1989-01-25 | — | — | EP | disclosed |
| EP-0192067-B1 | DISAZO DYES | BAYER AG (DE) | 1988-06-01 | — | — | EP | disclosed |
| EP-0158882-B1 | TRIPHENEDIOXAZINE DYES | BAYER AG (DE) | 1987-12-16 | — | — | EP | disclosed |
| EP-0235729-A2 | Reactive dyes | BAYER AG (DE) | 1987-09-09 | — | — | EP | disclosed |
| EP-0203505-A1 | Disazo metal complex dyes | BAYER AG (DE) | 1986-12-03 | — | — | EP | disclosed |
| US-4621138-A | Triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0192067-A1 | Disazo dyes | BAYER AG (DE) | 1986-08-27 | — | — | EP | disclosed |
| EP-0186812-A2 | Reactive dyes | BAYER AG (DE) | 1986-07-09 | — | — | EP | disclosed |
| EP-0158882-A2 | Triphenedioxazine dyes | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0128316-A1 | Reactive disazo dyes | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| EP-0128340-A1 | Reactive disazo dyes | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| US-4007164-A | FIBER-REACTIVE, CELLULOSE, WOOL | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |