Formic Acid

Formic Acid

SCHEMBL9009952

Cc1ccc(O)c(C)c1C.O=CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.46
ATM Q13315 1/20 0.46
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
MAOB P27338 1/20 0.36
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 2/20 0.35
MAPK1 P28482 1/20 0.35
SCN5A Q14524 1/20 0.35
HTR1D P28221 1/20 0.35
HTR1B P28222 1/20 0.35
GAA P10253 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HTT P42858 1/20 0.34
MAPT P10636 2/20 0.34
ERN1 O75460 3/20 0.33
MCL1 Q07820 1/20 0.33
TDP2 O95551 1/20 0.33
NSD2 O96028 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30388902 0.87 TRPA1 (0.57) TRPA1ATMESR1ESR2MAOB
SCHEMBL207038 0.87 TRPA1 (0.57) TRPA1ATMESR1ESR2MAOB
Phosphine SCHEMBL1067227 0.85 TRPA1 (0.55) TRPA1ATMESR1ESR2MAOB
Ammonia Solution, Strong SCHEMBL1065150 0.85 TRPA1 (0.55) TRPA1ATMESR1ESR2MAOB
Hydrochloric Acid SCHEMBL6039932 0.82 TRPA1 (0.52) TRPA1ATMESR1ESR2MAOB
Acetic Acid SCHEMBL6557428 0.81 TRPA1 (0.46) TRPA1ATMESR1ESR2MAOB
Dimethylamine SCHEMBL675006 0.80 TRPA1 (0.50) TRPA1ATMESR1ESR2MAOB
Formic Acid SCHEMBL9009940 0.79 TRPA1 (0.77) TRPA1ATMESR1ESR2TP53
Alcohol SCHEMBL28492687 0.78 TRPA1 (0.48) TRPA1ATMESR1ESR2TP53
SCHEMBL16852427 0.78 TRPA1 (0.48) TRPA1ATMESR1ESR2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0527642-B1 Process for simultaneously producing lactone and aromatic carboxylic acid MITSUBISHI GAS CHEMICAL CO (JP) 1996-11-06 EP disclosed
US-5278321-A Process for simultaneously producing lactone and aromatic carboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1994-01-11 US disclosed
EP-0527642-A1 Process for simultaneously producing lactone and aromatic carboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-02-17 EP disclosed