Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 7/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010132 | 0.92 | TTPA (0.56) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9259589 | 0.91 | TTPA (0.46) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9010228 | 0.87 | PTGS1 (0.57) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9255238 | 0.82 | TTPA (0.50) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9250008 | 0.82 | TTPA (0.56) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9010324 | 0.80 | TTPA (0.51) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9254482 | 0.80 | TTPA (0.56) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9252607 | 0.79 | TTPA (0.57) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9257632 | 0.79 | PTGS1 (0.54) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9427451 | 0.79 | TTPA (0.53) | TTPAALOX5PTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740936-A2 | Use of benzopyran derivatives for the manufacture of medicaments for the treatment of diseases connected with the sodium independent Cl-/HCO3- exchanger | ADIR ET COMPAGNIE (FR) | 1996-11-06 | — | — | EP | disclosed |
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |