Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259100 | 0.90 | TTPA (0.47) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL9313495 | 0.90 | TTPA (0.44) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9427643 | 0.90 | TTPA (0.42) | TTPAALOX5KMT2APTGS1PTGS2 | |
| SCHEMBL9427829 | 0.87 | PTGS1 (0.56) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9428287 | 0.86 | PSEN1 (0.54) | TTPAALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL9312779 | 0.86 | PSEN1 (0.52) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9251381 | 0.86 | PSEN1 (0.45) | TTPAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9314876 | 0.84 | TTPA (0.55) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL9655667 | 0.84 | KMT2A (0.48) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL9010132 | 0.84 | TTPA (0.56) | TTPAALOX5KMT2AMEN1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290797-A | Benzopyran compounds | ADIR ET COMPAGNIE (FR) | 1994-03-01 | — | — | US | claimed |
| US-5290797-A | Benzopyran compounds | ADIR ET COMPAGNIE (FR) | 1994-03-01 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |