Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexanone Oxime SCHEMBL8106638 | 0.87 | TSHR (0.70) | TSHRCASP1KDM4ERAB9ARXFP1 | |
| Cyclohexanone Oxime SCHEMBL9425289 | 0.82 | TSHR (0.78) | TSHRCASP1KDM4ERAB9ARXFP1 | |
| Cyclohexanone Oxime SCHEMBL28084559 | 0.79 | TSHR (0.93) | TSHRCASP1KDM4ERAB9AKMT2A | |
| Cyclohexanone Oxime SCHEMBL8558306 | 0.78 | TSHR (0.70) | TSHRCASP1KDM4ERAB9ARXFP1 | |
| Cyclohexanone Oxime SCHEMBL1720578 | 0.77 | TSHR (0.88) | TSHRCASP1KDM4ERAB9ARXFP1 | |
| Cyclohexanone Oxime SCHEMBL3260818 | 0.77 | TSHR (0.88) | TSHRCASP1KDM4ERAB9ARXFP1 | |
| Methacrylic Acid SCHEMBL3175980 | 0.76 | TDP1 (0.44) | TSHRKDM4EALDH1A1 | |
| SCHEMBL3190316 | 0.76 | TSHR (1.00) | TSHRCASP1KDM4ERAB9AKMT2A | |
| Cyclohexanone Oxime SCHEMBL11884936 | 0.76 | TSHR (1.00) | TSHRCASP1KDM4ERAB9AKMT2A | |
| Cyclohexanone Oxime SCHEMBL37995 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741126-A2 | Process for the preparation of oxime methacrylates | RÖHM GMBH (DE) | 1996-11-06 | — | — | EP | disclosed |