SCHEMBL9010570

SCHEMBL9010570

C=C1[C@H](C)C/C(=C/C=C2\CCC[C@@]3(C)C2CCC3[C@H](C)CC)C[C@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
VDR P11473 10/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10125580 1.00 VDR (0.51) VDR
SCHEMBL10820227 0.95 VDR (0.54) VDR
SCHEMBL14489228 0.95 VDR (0.54) VDR
SCHEMBL14112577 0.95 VDR (0.54) VDR
SCHEMBL10125575 0.93 VDR (0.51) VDR
SCHEMBL10125530 0.93 VDR (0.51) VDR
SCHEMBL14728279 0.93 VDR (0.49) VDR
SCHEMBL14728295 0.93 VDR (0.49) VDR
SCHEMBL14617409 0.92 VDR (0.53) VDR
SCHEMBL15461644 0.90 VDR (0.50) VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8188064-B2 Reducing cell differentiation of adipocyte; reducing body fat WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-05-29 US disclosed